Skip to content
  • ΕλληνικάΕλληνικά
  • EnglishEnglish
  • Home
  • School/Administration
    • History
    • Assembly
    • Secretariat
    • Departments
      • Pharmaceutical Chemistry
      • Pharmaceutical Technology
      • Pharmacognosy-Pharmacology
    • Library
    • Scientific Advisory Board
    • Key objectives – vision
  • Personnel
    • Faculty
      • Professors
      • Associate Professors
      • Assistant Professors
      • Lecturers
    • Specialized Laboratory Teaching Staff
    • Specialized Technical Laboratory Staff
    • Administrative Staff
    • Emeritus Professors
    • Retired Professors
    • Honorary Doctors
    • External Faculty
    • Retired
  • Studies
    • Undergraduate Studies
      • Courses per Semester
    • Postgraduate Studies
      • Profile of the Programme
      • Courses
      • Industrial Pharmacy
      • Pharmaceutical Technology
      • Drug Development, Diagnostics and Therapeutics
      • Pharmacology and Therapeutics
      • Pharmacochemistry, Drug Development
    • Bulletin of Studies
    • Erasmus
  • Useful Links
  • International
School of Pharmacy

School of Pharmacy

Αριστοτέλειο Πανεπιστήμιο ΘεσσαλονίκηςAristotle University of Thessaloniki

  • ΕλληνικάΕλληνικά
  • EnglishEnglish
  • Home
  • School/Administration
    • History
    • Assembly
    • Secretariat
    • Departments
      • Pharmaceutical Chemistry
      • Pharmaceutical Technology
      • Pharmacognosy-Pharmacology
    • Library
    • Scientific Advisory Board
    • Key objectives – vision
  • Personnel
    • Faculty
      • Professors
      • Associate Professors
      • Assistant Professors
      • Lecturers
    • Specialized Laboratory Teaching Staff
    • Specialized Technical Laboratory Staff
    • Administrative Staff
    • Emeritus Professors
    • Retired Professors
    • Honorary Doctors
    • External Faculty
    • Retired
  • Studies
    • Undergraduate Studies
      • Courses per Semester
    • Postgraduate Studies
      • Profile of the Programme
      • Courses
      • Industrial Pharmacy
      • Pharmaceutical Technology
      • Drug Development, Diagnostics and Therapeutics
      • Pharmacology and Therapeutics
      • Pharmacochemistry, Drug Development
    • Bulletin of Studies
    • Erasmus
  • Useful Links
  • International

Advanced Course on Xenobiotic Metabolism

Description: 1. Eleni Rekka - Introduction: Purpose of xenobiotic metabolism in the organism. Organs and xenobiotic metabolising enzyme systems of the organism. Phases of xenobiotic metabolism (I, II and III). Biointoxication, biodetoxication. –Cytochrome P450 enzyme superfamily: Structure, binding, type I, II and reverse type II spectra, Catalytic circle, Evolution, division and catalytic activity. Induction and inhibition. Relation with peroxisomes. Cytochrome P450 enzymes in the metabolism of xenobiotics. –Non cytochrome P450 enzymes in the metabolism of xenobiotics: Carboxyesterases, Glutathione-S-transferases, Epoxide hydrolases. –Drug design based on xenobiotic metabolism. 2. Panagiotis Kourounakis -Xenobiotic oxidations by the flavin containing monoxygenases (FMO): Structure, characteristics, substrates, inducers, examples. –Aminoxidases and drug metabolism: Structure, specificity, distribution in the organism, regulation and turnover. Xenobiotic primary amines. Metabolism of xenobiotics via primary amines. Inhibition by acetylenic compounds and mechanism. –Prodrugs, chemical delivery systems. –Stress and xenobiotic metabolism. –Brain and xenobiotic metabolism.
ECTS: 10
Hours: 6
Semester: 1

Professor:
Advanced Course on Xenobiotic Metabolism

Post navigation

Advanced Medicinal Chemistry: Drug Design, Selected Drug Synthesis (postgraduate course)
Methods of Drug Synthesis with Emphasis to Heterocyclic Medicinal Chemistry (postgraduate course)

Top news


More ...

Pages

  • User Feedback
  • Quality Policies of AUTh
  • Πολιτική Ποιότητας Τμήματος Φαρμακευτικής Α.Π.Θ.

Contact

Aristotle University of Thessaloniki
School of Pharmacy
University Campus, 54124
Thessaloniki, Greece
Τ: +302310997633
+302310997623
+302310997613
+302310998880
E: info@pharm.auth.gr

Chair of the School: Kachrimanis Kyriakos

Secretary: Symeonidou Konstantia

© 2023 School of Pharmacy

Powered by websites.auth