Director: Markopoulou Aikaterini
The Pharmaceutical Analysis Laboratory is located on the 2nd floor of the building.
Educational and Research Focus
Laboratory members contribute to the undergraduate curriculum by teaching the courses Pharmaceutical Analysis I, Pharmaceutical Analysis II, and Analytical Chemistry. At the postgraduate level, they teach Advanced Pharmaceutical Analysis, Industrial Pharmacy, Drug Development, Diagnostics, and Therapeutics in the Department of Pharmacy.
The primary research interests of the laboratory include:
- Development and validation of analytical methods for the detection of impurities, by-products, enantiomers, genotoxic impurities, etc., in active pharmaceutical ingredients (APIs) and final drug products
- Analysis of pharmaceutical compounds and their metabolites in biological samples using advanced separation techniques
- Study and identification of degradation products formed under forced degradation conditions
- Stability testing of pharmaceutical compounds in various formulations
- Investigation of dissolution profiles of solid pharmaceutical forms
- Exploration and enhancement of drug-likeness properties of compounds
- Design and development of multiparametric separation systems for understanding the retention mechanisms of pharmaceutical substances via liquid chromatography
Research Equipment
The laboratory is equipped with a range of advanced instruments, including:
- Dual-beam UV-Vis spectrophotometer
- Near-infrared (NIR) spectrophotometer
- Spectrofluorimeter
- HPLC systems with UV-Vis photodiode array (PDA), evaporative light scattering (ELSD), fluorometric, and electrochemical detectors
- HPLC system with electrospray ionization mass spectrometry (ESI-MS) detector
- Sample pretreatment systems including solid-phase extraction (SPE) and solvent evaporation systems
Services Offered
The laboratory provides a range of services to external partners, including:
- Development and validation of analytical methods
- Quantitative analysis of pharmaceutical compounds and metabolites in biological fluids
- Quality control testing of pharmaceutical formulations
- Stability and degradation studies of pharmaceutical products